What is Diabetes Type 1?
Diabetes is the disease affecting the metabolism of glucose that comes from the food we consume and carried to the cell by a hormone known as insulin. Diabetes develops when the body either is unable to properly prepare or respond to insulin. Type 1 is known as insulin dependent or juvenile diabetes, whereas the pancreatic ability to produce insulin is reduced. Insulin is produced by the beta cells of the pancreas. In Diabetes Type 1, the body’s own defense system can damage beta cells and without enough insulin, glucose gets accumulated in the bloodstream and may lead to hyperglycemia. Stem cells are the cells responsible for developing an entire human body from a two-celled embryo; due to their unlimited divisions and ability to differentiate into different cell lineages. Stem cells have been harnessed by specialized technology to isolate them outside the human body, concentrate them and implant them back into the body. Thus, stem cell treatment for Diabetes involves administration of concentrated cells in the targeted areas in which they can colonize, adapt properties, and initiate some of the lost functions compromised by the disease. Various data is available suggesting in-vitro differentiation of stem cells into insulin producing beta cells creating a microenvironment to initiate secretion of immune cells to counteract the abnormal autoimmunity of the individual.
Treatment of Diabetes Type 1 at Cellebration Life Sciences, Inc.
At Cellebration, we have mastered the technology for isolating a maximum number of viable stem cells from either autologous (own) cells or allogeneic (donor) cells to treat patients with Diabetes Type 1. We are a licensed, private organization with a highly technologically equipped specialized facility under development designed to isolate and enrich the viable cell stems which will be infused into the patient. These cells are administered through one of the methods after a considerable analysis of the patient’s unique history and medical professional’s advice.
- Local Administration: – In this mode, cells are infused directly at the targeted site through a catheter-based delivery mode.
- Intravenous Administration: – In this delivery mode, cells are infused into the peripheral veins to expand blood volumes in the system, to ensure that the maximum number of cells are reaching the targeted area.
Once infused back in the body, these cells can be repopulated at the damaged parts of the pancreas. Through their strong paracrine effects, they differentiate into lost or damaged (insulin producing cells) beta cells, and initiate secretions in new cells.