What is Spinal Cord injury?
Spinal Cord Injury is severe damage to the human spinal cord. There are three different segments of the neural tissue leading to the severe form of motor and sensory loss. This kind of damage can be differentiated as: death of neurons within the spinal cord, disruption of neuronal pathways due to damaged cells, destruction of the protective myelin sheath carrying nerve signals from the brain to different organs of the body.
In general, a spinal cord injury is resultant due to the severe damage to different parts of the spinal cord such as vertebral column, ligaments, or spinal disks. In most reported cases of SCI, damage can be due to trauma or disease. Apart from the physical damage and complete dependency on caregivers, the SCI can be emotionally damaging as well. Due to dependency even on basic mobility, negative attitudes and frequent mood swings can lead the patient to be excluded from social participation. Thus, more than 30% of the reported cases of SCI showed significant signs of depression and negative impact on overall health. The human spinal cord is a fragile bridge connecting the brain with the other organs of the body. The spinal cord is encased in the protective covering of spinal vertebrae in the spinal column to prevent its damage from shock or injury. The central nervous system which is the brain and the spinal cord is made up of millions of cells, which coordinate and communicate to pass on the information from the brain to other organs of the body via the spinal cord. This information is passed in the form of electrical signals which is then decoded by the specific organ. Each neuron is made up of a cellular body with a long slender projection called a nerve fiber. These fibers are attached to the other fibers to form a dense network of cells. In general, neurons carrying messages down the cord from the brain to other organs of the body are known as Motor Neurons. These neurons control the muscles of important internal organs of the body such as the heart, stomach, and intestine. The neurons traveling up the cord to the brain are known as Sensory Neurons, carrying sensory information from the skin, joints, and muscles to control our ability to sense, touch and regulate body temperature. These neurons are insulated from the outer side by the coating of Oligodendrocytes and myelin sheath. These cells insulate the neurons to protect them from sudden damage and shock. If any of the above types of cells are affected due to sudden damage such as shearing, laceration, stretching or shock, then the network of cells is disturbed and prevents the passage of information between the brain and the spinal cord.
Treatment for Spinal Cord injury at Cellebration Life Sciences, Inc.
At Cellebration, we have mastered the technology for isolating the maximum number of viable stem cells from either the autologous sources of your own body or allogeneic with a matched donor to treat various patients with Spinal Cord injury. We are a licensed, private organization with a highly technologically equipped specialized facility under development designed to isolate and enrich the viable cell stems which will be infused into the patient. Stem cell treatment for patients with Spinal Cord injury involves administration of concentrated cells in the targeted area to form colonies, adapt the properties of resident stem cells and initiate some of the lost functions that have been compromised by the disease or injury. These cells are administered through one of two methods after a considerable analysis of the patient’s unique history and medical professional’s advice.
- Intrathecal Administration:-In this mode, cells are infused in the cerebrospinal fluid through the subarachnoid spaces of the spinal canal.
- Intravenous Administration:- Through this mode, cells are infused through the veins to expand blood volumes in the system, to ensure that the maximum number of cells are reaching the targeted area.
Once infused back in the body, these cells can be repopulated at the damaged parts of the organ Through their strong paracrine effects, they differentiate into lost or damaged cells. Thus with our standardized, broad based and holistic approach, it is now possible to obtain noticeable improvements in patients with Spinal Cord injuries for symptoms as well as their functional abilities.
